Preimplantation Genetics PGD/PGS Plans
“Preimplantation genetic screening” (PGS) is used when the parents have no known mutations that are expected to cause disease in the embryo, and are presumed to have a normal karyotype. PGS tests the embryo to confirm that the embryo has an even number of chromosomes.
PGS involves a standard biopsy procedure performed on embryos in conjunction with an in-vitro fertilization (IVF) cycle, prior to implantation. This allows screening of the embryos for chromosomal abnormalities before being transferred in an IVF cycle.
Chromosomal abnormalities can lead to failed implantation or early loss of pregnancy. Screening enables specialists to identify embryos with normal structure and having the best chance for successful implantation.
Who Will Benefit From PreImplantation Genetic Screening?
- Patients who have experience recurrent miscarriages
- Multiple IVF failures
- Advanced maternal age (>35)
- Desire to limit number of embryos transferred
- Couples with severe male factor infertility